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Alzheimer's Interview with Brian Appleby, MD

CLEVELAND -- Brian Appleby, MD, a geriatric psychiatrist at University Hospitals Case Medical Center, discusses young onset Alzheimer's in the wake of legendary Tennessee women's basketball coach Pat Summitt's death from the disease at age 64. Symptoms include memory and recollection problems and changes in personality and behavior. He says the life expectancy for an young onset patient is eight to ten years after initial symptoms.

He also discusses prevention, citing lifestyle in addition to genetics as a cause, recommending a low fat, low cholesterol diet, exercise, and social and mental engagements to help. He says Pat Summit can help raise awareness for the disease the same way President Ronald Reagan did before his death in 2004 and the movie "Still Alice" did when it won the Oscar in 2015.

Rooftop garden in full bloom at UH Rainbow Babies & Children’s Hospital (VIDEO)

CLEVELAND – Patients, families, staff and the community gathered today to experience one of only a few hospital rooftop gardens in the country at University Hospitals Rainbow Babies & Children’s Hospital (UH Rainbow). Angie’s Garden, a 7,500-square-foot healing garden, is a place where all patients and their families can be outside, away from the clinical environment, in their own natural oasis. A butterfly release of about 100 butterflies kicked off today’s rooftop event.
“Angie’s Garden is in full bloom, with a beautiful color palate that includes various scents and textures found in a sensory garden,” says Kristina Arthur, UH Rainbow’s horticulturalist. “It is amazing to watch a family enter the garden and see an instant and noticeable shift from patients and caregivers to simply kids and parents.”
Highlights of the garden include:
  • Rainbow canopy that casts prisms of light across the space
  • Bird and running water sound areas
  • Full-size baby giraffe sculpture
  • 40-foot living wall tapestry
  • Kaleidoscope planter
  • Telescope overlook with a breathtaking view of Cleveland’s skyline and surrounding vistas
Angie’s Garden is part of the Angie Fowler Adolescent & Young Adult Cancer Institute (Angie’s Institute) at UH Rainbow, founded in 2012 with a generous $17 million gift from Char and Chuck Fowler in honor of their daughter Angie. Angie’s Institute – fully integrated with UH Seidman Cancer Center and Case Comprehensive Cancer Center – is specifically designed to improve outcomes for the teen and young adult patient population. Angie’s Institute outpatient center opened in spring 2014 on the UH Rainbow Horvitz Tower 8th floor. The newly renovated space is one of the first in the country to offer separate, age-appropriate areas, technologies and amenities for babies/children and adolescents/young adults. 

Meet the Beadles (VIDEO/AUDIO)

CLEVELAND -- Meet the Beadles, the Fab Four, quadruplets born May 1st at UH MacDonald Women's Hospital who have spent their first  six weeks in the NICU at UH Rainbow Babies & Children's Hospital. Born eight weeks premature, (in order) it's Gia, Leo, Lea, and Geo who have caused this Beadlemania.

Lea and Geo just went home but parents Melissa and Bob Beadle, who live in the Youngstown area, will stay at the Ronald McDonald House in University Circle until the other two go home, closer to their due date of July 24th.

B-Roll of Aparna Bole, MD (VIDEO)

CLEVELAND -- Video of Aparna Bole, MD, Sustainability Manager at University Hospitals and Pediatrician at University Hospitals Rainbow Babies & Children's Hospital.

Progesterone Helping Bring Premature Births Down 21% in Ohio (VIDEO/AUDIO)

CLEVELAND -- With an infant mortality rate of 6.41 (first year deaths per 1000 live-born infants), the United States ranks behind 28 other developed nations, with preterm births (before 37 weeks of gestation) the leading cause of infant mortality.

"Our hope is that we put ourselves out of business," says Michele Walsh, MD, Chief of Neonatology at University Hospitals Rainbow Babies & Children's Hospital, "that we don't have tiny, premature babies, that we don't have infants with heart defects or other defects that put them in desperate situations."

With the Ohio Perinatal Quality Collaborative, Rainbow and other Ohio hospitals have identified women with a previous preterm birth and have started them on the hormone progesterone early in the pregnancy, at about 16 weeks. The results are startling.

"Those women can have an over 50 percent reduction in having a second premature infant," says Dr. Walsh. "That is amazing. We've never seen that."

Progesterone is a naturally occurring hormone that plays a key role in pregnancy, helping the uterus grow and preventing contractions that lead to premature births. Progesterone also helps get oxygen to growing babies. If progesterone is low, boosting progesterone with treatments starting at 16 weeks lowers the risk premature infants.

Ohio's infant mortality rate of 7.8 exceeds the national average and puts Ohio at number twelve in the country. Across the state, African-American women who've had a previous premature birth are at the highest risk of delivering babies before 32 weeks and their treatment has lead to a 21% overall reduction across the state.

"We have a huge problem with infant mortality in Ohio and prematurity is the driver of that," says Dr. Walsh. "So if we can impact this across all of Ohio, we can really change things for babies and families."

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