News Releases

Thursday, September 25, 2014

New research outlines promising therapies for small cell lung cancer

CLEVELAND –  Two recently published studies by a research team at University Hospitals (UH) Case Medical Center Seidman Cancer Center have the potential to advance treatments for small cell lung cell cancer (SCLC). This aggressive form of lung cancer has seen no treatment advances in 30 years and “is a disease in urgent need of new drug therapies,” write the study’s authors.
 
“In small cell lung cancer, which impacts about 30-40,000 people each year in the United States, there has been no therapeutic progress and very little research,” says Afshin Dowlati, MD, lead author and Director of the Center for Cancer Drug Development at UH Seidman Cancer Center. “Additionally, there are no approved targeted therapies for the disease. These studies lay the foundation for future research aimed at finding important new treatments for this highly malignant cancer.”
 
A study titled, RET Mutation and Expression in Small Cell Lung Cancer, was published in the September issue of Journal of Thoracic Oncology and found a new mutation in SCLC which may play a role in the disease’s development. The researchers found that the genetic mutation, called RET (rearranged during transfection), was linked to rapid cell growth.


Wednesday, August 27, 2014

University Hospitals Case Medical Center partners with ImPACT Applications to offer comprehensive concussion management program

CLEVELAND – University Hospitals (UH) Case Medical Center has entered into a partnership with ImPACT Applications, Inc., developer of the ImPACT© Test and ImPACT Concussion Management Model, to improve concussion prevention, identification and treatment for athletes and individuals in the Cleveland area.
 
UH is using ImPACT neurocognitive baseline and post-injury testing in all schools with UH physicians and/or athletic trainers. UH plans on conducting 10,000 baseline tests on high school student athletes.  As part of the implementation, the UH clinical team will participate in intensive training on ImPACT test administration and the application of all aspects of ImPACT's Concussion Management Model. UH is working toward having 10 physicians as Certified ImPACT Consultants (CICs) and 10 ImPACT Trained Athletic Trainers (ITATs), in recognition of the training and education they will receive.


Thursday, August 21, 2014

UH Case Medical Center’s Dr. Parikh authors SCAI paper on treatment of renal artery stenosis

CLEVELAND – Renal artery stenting to open blockages in the kidney arteries may benefit patients who have historically been excluded from modern clinical trials, according to new recommendations for renal artery stenosis e-published in Catheterization and Cardiovascular Interventions today by the Society for Cardiovascular Angiography and Interventions (SCAI).

University Hospitals Case Medical Center’s Sahil Parikh, MD, Director, Interventional Cardiology Fellowship Program and Professor of Medicine, Case Western Reserve University School of Medicine was the lead author on the paper that details possible assessment and treatment guidelines for renal artery disease.
 
Blockages in the kidney (renal) arteries are often asymptomatic, but may lead to high blood pressure or worsening of high blood pressure control. If left untreated, the disease can cause kidney failure and heart failure. Optimal medical therapy remains the preferred first-line treatment. 


Wednesday, August 13, 2014

UH Case Medical Center begins offering new treatment for obstructive sleep apnea

CLEVELAND – University Hospitals (UH) Case Medical Center is the first in Ohio and among the first in the United States to begin offering a new FDA-approved treatment for obstructive sleep apnea (OSA).
 
This first-of-its-kind treatment consists of a small implantable system called Inspire™ Upper Airway Stimulation (UAS) therapy. It has been clinically proven to significantly reduce sleep apnea events and improve quality of life for people who cannot tolerate continuous positive airway pressure (CPAP).
 
UH Case Medical Center was one of the clinical study sites for the Stimulation Therapy for Apnea Reduction (The STAR Trial) study, and the findings were published in the New England Journal of Medicine (Jan. 9, 2014).  The STAR trial results showed that Inspire therapy reduced apnea events by 68 percent and significantly improved key quality of life measures.


Thursday, August 07, 2014

Study validates new approach to high blood pressure

CLEVELAND – It truly could be mind over matter after all.
 
University Hospitals Case Medical Center’s Richard Josephson, MD, recently released trial results in a study published in Psychosomatic Medicine that discusses mindfulness-based stress reduction (MBSR) for hypertension.
 
Nearly 60 million adults in the United States have high blood pressure in the pre-hypertensive range. Current treatment guidelines recommend lifestyle changes such as diet, exercise and overall weight loss.
 
According to the new study, these changes can be dramatically augmented by MBSR as the methodology includes stress reduction, meditation for depression and anxiety and structured treatment management program.



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