Tuesday, December 08, 2015
CLEVELAND – Researchers from the Department of Neurological Surgery at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center recently received multi-year, multi-million dollar grants from the National Institutes of Health (NIH) for studies in Parkinson’s disease, stroke, and brain cancer.
Barry J. Hoffer, MD, PhD, adjunct professor of neurosurgery at Case Western Reserve and a member of the Department of Neurosurgery at UH Case Medical Center, received a 3-year,
$1 million grant for continuing research into gliptins for the treatment of Parkinson’s disease. Gliptins, widely used in the effective treatment of type 2 diabetes to safely regulate blood glucose levels, also have been found to provide neurological protection in Parkinson’s. In rat studies, gliptins increase levels of hormones called incretins which reduced Parkinson’s symptoms.
The new grant will enable Dr. Hoffer and colleagues to continue their evaluation of gliptins as a new treatment strategy for Parkinson’s in mouse models.