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New research uses deep sequencing of breast cancer tumors to predict clinical outcomes in patients after single dose of therapy
Friday, December 13, 2013

New research uses deep sequencing of breast cancer tumors to predict clinical outcomes in patients after single dose of therapy

CLEVELAND – New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.
 
Results showed that through deep genome sequencing, a reduction in the most commonly mutated genes in breast cancer could be observed after just one dose of preoperative therapy. Deep sequencing is a process that involves sequencing the same region multiple times to identify mutations within tumors that have an importance in cancer evolution. These new findings were presented during the 2013 San Antonio Breast Cancer Symposium.

Harrington Discovery Institute at UH Case Medical Center announces grant funding to physician-scientists at major academic medical centers nationwide to support new drug development
Wednesday, December 11, 2013

Harrington Discovery Institute at UH Case Medical Center announces grant funding to physician-scientists at major academic medical centers nationwide to support new drug development

CLEVELAND – The Harrington Discovery Institute at University Hospitals (UH) Case Medical Center has announced the 2014 recipients of Harrington Scholar-Innovator Awards. The awards will support drug discovery efforts of great promise at renowned institutions across the nation.
 
For the past decade, American Medicine has been challenged in developing new drugs that would improve on standard of care. Lacking knowhow and industry support, many discoveries are unable to advance into the clinical realm. Aimed at addressing this critical issue, the Harrington Discovery Institute (HDI), established in 2012, is a national initiative dedicated to physician-scientists, enabling them to transform breakthrough insights into novel medicines. The institute has become the catalyst for a new national model that aligns, through structure and mission, for-profit and nonprofit resources to create a dedicated system for drug development. 

UH Rainbow Babies & Children’s Hospital Only Northeast Ohio Hospital Named to Leapfrog’s Top Children’s Hospital Honor Roll
Tuesday, December 03, 2013

UH Rainbow Babies & Children’s Hospital Only Northeast Ohio Hospital Named to Leapfrog’s Top Children’s Hospital Honor Roll

CLEVELAND, Ohio – University Hospitals Rainbow Babies & Children’s Hospital (UH Rainbow) is one of only 13 children’s hospitals in the country – and the only one in northern Ohio – to receive the Top Children’s Hospital distinction from The Leapfrog Group. This national recognition honors UH Rainbow for its exemplary performance in patient safety, quality initiatives and highly reliable care.  
 
“Our physicians and staff are dedicated to providing the highest quality of care in the safest environment that uniquely caters to babies and children, and their families,” says Patricia DePompei, RN, MSN, President, UH Rainbow and UH MacDonald Women’s Hospital.

Brain bypass surgery gives young man his life back at University Hospitals
Wednesday, November 27, 2013

Brain bypass surgery gives young man his life back at University Hospitals

CLEVELAND – On February 14, 2013, Eric Wagner told his wife to call 9-1-1 because he was feeling the worst that he had ever felt. He was rushed by EMS to University Hospitals (UH) Ahuja Medical Center, and then airlifted to UH Case Medical Center, where brain scans showed that he had a ruptured aneurysm, a leaking blister on a blood vessel that was letting blood flow into his brain.
              
To make matters worse, the aneurysm was located deep in his brain. Fortunately, UH neuroradiologist Jeffrey Sunshine, MD, PhD, closed off the blister with a series of small titanium coils that stemmed the blood flow to that weakened area.

Harrington Discovery Institute’s Dr. Jonathan Stamler earns AHA Distinguished Scientist Award
Thursday, November 21, 2013

Harrington Discovery Institute’s Dr. Jonathan Stamler earns AHA Distinguished Scientist Award

CLEVELAND – Jonathan Stamler, MD, Director of the Harrington Discovery Institute at University Hospitals (UH) Case Medical Center, has received the 2013 American Heart Association Distinguished Scientist Award at the association’s annual conference in Dallas, TX.
 
This prestigious honor, the highest bestowed by the American Heart Association, recognizes individuals whose work has significantly advanced the understanding of cardiovascular disease and stroke. An internationally renowned physician-scientist, Dr. Stamler is recognized for the discovery of a universal mechanism by which the gas nitric oxide affects cellular function in biology.

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